产品货号:
Z15110
中文名称:
Dysferlin/DYSF抗体
英文名称:
Anti-Dysferlin/DYSF Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-Dysferlin/DYSF Antibody |
指标别名 | Dysferlin;FER1L1;LGMD2B;LGMDR2;MMD1;DYSF |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | WB,ICC/IF,IHC,FCM,ELISA |
基因名称 | DYSF |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | E.coli-derived human DYSF recombinant protein (Position:E51-H747). |
实际分子量 | 280KD |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | Immunogen affinity purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | Dysferlin also known as dystrophy-associated fer-1-like protein is a protein that in humans is encoded by the DYSF gene.The protein encoded by this gene belongs to the ferlin family and is a skeletal muscle protein found associated with the sarcolemma.It is involved in muscle contraction and contains C2 domains that play a role in calcium-mediated membrane fusion events,suggesting that it may be involved in membrane regeneration and repair.In addition,the protein encoded by this gene binds caveolin-3,a skeletal muscle membrane protein which is important in the formation of caveolae.Specific mutations in this gene have been shown to cause autosomal recessive limb girdle muscular dystrophy type 2B (LGMD2B) as well as Miyoshi myopathy.Alternative splicing results in multiple transcript variants. |
Uniprot ID | O75923 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot. |
基因名全称 | dysferlin |
蛋白名全称 | Dysferlin |
推荐稀释比 | Western blot (WB) 1:500~2000 Immunohistochemistry (IHC) 1:50~400 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50~400 Flow cytometry (FCM) 1~3μg/1×106 cells Enzyme linked immunosorbent assay (ELISA) 1:100~1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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